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Development of Ketoacidosis During the Perioperative Period: an Observational Study 'The DKAP Study'

NCT05225467 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 58

Last updated 2023-07-20

No results posted yet for this study

Summary

Rationale:

During perioperative period, prolonged starvation, surgical stress, acute complications (e.g. infection) and medication changes all promote ketone generation, therefore increasing the risk of ketoacidosis. At present, there is no literature concerning the ketone production in patients undergoing cardiac surgery, regardless of the diabetes status.

Objectives:

The objectives of this study are to explore the change in blood ketone level during the perioperative period in patients with and without diabetes, to observe the incidence of perioperative ketoacidosis, and to investigate therapy and outcome of patients with perioperative ketoacidosis.

Conditions

  • Ketosis
  • Keto Acidosis
  • Ketoses, Metabolic
  • Ketosis, Diabetic
  • Peri-operative
  • Diabetes Mellitus

Sponsors & Collaborators

  • Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

    lead OTHER

Principal Investigators

  • Jeroen Hermanides, dr · Amsterdam Univeristy medical Center

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-03-15
Primary Completion
2023-03-17
Completion
2023-03-18

Countries

  • Netherlands

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05225467 on ClinicalTrials.gov