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MUA to Treat Postoperative Stiffness After Total Knee Arthroplasty

NCT02739035 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 130

Last updated 2023-11-21

Study results available
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Summary

Compare the outcome following manipulation under anesthesia for stiffness in a randomized controlled fashion with one group receiving IV dexamethasone and oral celecoxib at the time of manipulation to a control group receiving manipulation alone.

Outcomes will include pain, range of motion, as well as subjective outcome scores.

Conditions

  • Stiffness Following Total Knee Arthroplasty

Interventions

DRUG

Dexamethasone

8 mg of IV dexamethasone immediately before MUA.

DRUG

Celecoxib

2 weeks per mouth of celecoxib (200 mg daily)

Sponsors & Collaborators

  • Knee Society

    collaborator OTHER

  • Mayo Clinic

    lead OTHER

Principal Investigators

  • Abdel Matthew, M.D. · Mayo Clinic

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-04-30
Primary Completion
2022-12-31
Completion
2022-12-31
FDA Drug
Yes

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02739035 on ClinicalTrials.gov