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Grape and Pomegranate Polyphenols in Postprandial Glucose and Related Parameters

NCT02710461 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2017-03-28

No results posted yet for this study

Summary

The aim of this is study is to evaluate the acute effect of grape and pomegranate polyphenols in the modulation of markers of metabolic syndrome. Most of the previous works about polyphenols have only considered a fraction of polyphenols, i.e., extractable polyphenols. As a consequence, an important amount of dietary polyphenols, the so-called non-extractable polyphenols are ignored. In contrast, the effect of both extractable and non-extractable polyphenols will be considered in this study. Furthermore, the effect of both polyphenols as present in the food matrix and metabolites derived from microbial fermentation will be evaluated.

Conditions

  • Subjects With Abdominal Obesity

Interventions

DIETARY_SUPPLEMENT

Mixture of grape pomace and pomegranate pomace

Oral Glucose Tolerance Test

DIETARY_SUPPLEMENT

Mixture of grape pomace and pomegranate pomace

Oral Glucose Tolerance Test right after taking the mixture of grape and pomegranate polyphenols

DIETARY_SUPPLEMENT

Mixture of grape pomace and pomegranate pomace

Oral Glucose Tolerance Test ten hours after taking the mixture of grape and pomegranate polyphenols

Sponsors & Collaborators

  • Ministerio de Economía y Competitividad, Spain

    collaborator OTHER_GOV

  • National Research Council, Spain

    lead OTHER_GOV

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
40 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-03-31
Primary Completion
2016-10-31
Completion
2016-12-31

Countries

  • Spain

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02710461 on ClinicalTrials.gov