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Hyperglycemia and Mitochondrial Function in The Endothelium of Humans

NCT02682342 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 35

Last updated 2025-01-10

Study results available
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Summary

In this study, the investigators will test the hypothesis that acute in vivo exposure to hyperglycemia increases mitochondrial network fragmentation and mitochondrial reactive oxygen species production (ROS) production in human arterial endothelial cells.

Conditions

Interventions

OTHER

75 g glucose solution

This is the same as the standard oral glucose challenge dose and route given clinically

Sponsors & Collaborators

  • Medical College of Wisconsin

    lead OTHER

Principal Investigators

  • Micahel E Widlansky, MD · Medical College of Wisconsin

Eligibility

Min Age
21 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-03-09
Primary Completion
2022-02-28
Completion
2022-11-22

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02682342 on ClinicalTrials.gov