Cerebral Responses to Insulin Induced Hypoglycemia
NCT02747680 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 266
Last updated 2021-02-03
Summary
This research study is designed to investigate the effect of hypoglycemia (low blood sugar) on blood flow to and biochemistry in the brain.
Conditions
- Type 1 Diabetes
- Healthy
- Hypoglycemia Unawareness
Interventions
- OTHER
-
hypoglycemia (low blood sugar) in MRI
hypoglycemia (low blood sugar) in MRI
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Elizabeth Seaquist, MD · University of Minnesota
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- DIAGNOSTIC
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2004-01-31
- Primary Completion
- 2020-03-31
- Completion
- 2020-12-31
Countries
- United States
Study Locations
More Related Trials
-
Naltrexone and Hypoglycemia in Type 1 Diabetes
NCT01053078 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Naloxone, Hypoglycemia and Exercise
NCT03149770 ·Status: COMPLETED ·Phase: PHASE2
-
Insulin-based Strategies to Prevent Hypoglycemia During Two Types of Exercise
NCT03845114 ·Status: COMPLETED ·Phase: NA
-
Diagnosing and Treating Low Blood Sugar Levels
NCT00001276 ·Status: RECRUITING
-
Hypoglycemia in Hospitalized Patients
NCT02228642 ·Status: COMPLETED
-
Efficiency of Two Glucose Sampling Protocols for Maintenance of Euglycemia
NCT00993057 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Liver Glycogen and Hypoglycemia in Humans
NCT03241706 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
The Role of Endogenous Lactate in Brain Preservation and Counterregulatory Defenses Against Hypoglycemia
NCT02308293 ·Status: COMPLETED ·Phase: NA
-
Effect of Fasting on Insulin-induced Hypoglycemia Counterregulation in Healthy Humans
NCT04392843 ·Status: COMPLETED ·Phase: NA
-
Sympathetic Nerve Activity During Hypoglycemia and Exercise
NCT00608348 ·Status: COMPLETED ·Phase: NA
-
Adverse Effects of Systemic Hypoglycemia Exposure on Endothelial Function in Humans
NCT01660009 ·Status: TERMINATED ·Phase: NA
-
Consequences of Hypoglycemia on Intensive Care Unit (ICU) Patients
NCT00662922 ·Status: COMPLETED
-
Intensive Versus Nonintensive Insulin Therapy for Hyperglycemia After Traumatic Brain Injury
NCT02161055 ·Status: UNKNOWN ·Phase: PHASE4
-
Normoglycemia and Neurological Outcome
NCT01137773 ·Status: TERMINATED ·Phase: PHASE4
-
Investigating the Acute Effects of Increasing Glucagon Exposure in Healthy Participants
NCT06921824 ·Status: COMPLETED ·Phase: NA
-
Hypoglycemia and the Mineralocorticoid Receptor
NCT01394627 ·Status: COMPLETED ·Phase: NA
-
Insulin-based Strategies to Prevent Hypoglycemia During Exercise
NCT02631265 ·Status: COMPLETED ·Phase: NA
-
Effect of Naltrexone on Counterregulatory Mechanisms in Hypoglycemia
NCT01462227 ·Status: COMPLETED ·Phase: NA
-
Use of a Hyperinsulinemic-hypyglycemic Clamp to Study Hypoglycemia: a Method Development Study
NCT03839511 ·Status: COMPLETED
-
Analysis of Related Risk Factors of Hypoglycemia Consciousness Disorder
NCT04971070 ·Status: COMPLETED
-
Evaluation of the Effect of Hypoglycemia With PET and a Norepinephrine Transporter Ligand
NCT02056249 ·Status: COMPLETED
-
A Survey on Hypoglycaemia Among Insulin-treated Patients With Diabetes
NCT02230631 ·Status: COMPLETED
-
Hypoglycemia: Physician and Patient Perspectives
NCT01176656 ·Status: COMPLETED
-
Glycemia and Ischemia Reperfusion Brain Injury in Patients With Acute Cerebral Infarction Treated With Mechanical Thrombectomy
NCT05871502 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Disorders of Systemic Glucose Balance
NCT00006508 ·Status: COMPLETED ·Phase: NA