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Preoperative Glucose Infusion: a Novel Strategy to Improve Liver Function After Liver Resection

NCT00623662 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2018-04-03

No results posted yet for this study

Summary

The goal of the study is to determine whether intravenous glucose administration before liver resection preserves hepatic glycogen resulting in improved hepatic metabolic function after the operation.

We further investigate whether the benefit of avoiding preoperative fasting is more pronounced in patients undergoing more extensive liver resection.

Conditions

  • Hepatic Insufficiency
  • Liver Failure

Interventions

OTHER

Preoperative glucose infusion

Glucose infusion from 15:00 on the day before the operation until beginning of surgery.

OTHER

Preoperative normal saline infusion

Normal saline infusion from 15:00 on the day before surgery until beginning of the operation.

Sponsors & Collaborators

  • McGill University Health Centre/Research Institute of the McGill University Health Centre

    lead OTHER

Principal Investigators

  • Ralph Lattermann, MD PhD · Department of Anaesthesia, McGill University Health Centre

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-02-29
Primary Completion
2019-03-31
Completion
2019-03-31

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00623662 on ClinicalTrials.gov