Impact of Estrogen on Fear Extinction R61
NCT02673606 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 136
Last updated 2020-07-30
Summary
The goal of this project is to examine how estrogen may influence the resting-state connectivity and the extinction-induced activation of the fear extinction network.
Conditions
- Fear
- Fear; Examination, Phobic
Interventions
- DRUG
-
Estradiol 2Mg Tablet
one 2 mg dose of estradiol (obtained from Estrace® Tablets, 2.0 mg estradiol tablets, USP, Warner Chilcott),
- DRUG
-
Estradiol 4Mg Tablet
two 2 mg pills estradiol(obtained from Estrace® Tablets, 2.0 mg estradiol tablets, USP, Warner Chilcott),
- DRUG
-
Placebo Pills
inactive placebo pills
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Mohammed Milad, PhD · NYU School of Medicine
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- FEMALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2013-01-31
- Primary Completion
- 2019-04-15
- Completion
- 2019-04-15
- FDA Drug
- Yes
Countries
- United States
Study Locations
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