Estrogen Replacement to Reduce Risk of Neurologic Injury After Coronary Artery Bypass Graft Surgery
NCT00123539 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 334
Last updated 2016-07-29
Summary
The purpose of this study is to test whether perioperative estrogen replacement in postmenopausal women reduces the risk for neurologic injury after coronary artery bypass graft (CABG) surgery.
Conditions
- Coronary Disease
- Cardiovascular Diseases
- Heart Diseases
- Neurologic Manifestations
Interventions
- DRUG
-
Estrogen Replacement Therapy
- PROCEDURE
-
Surgery
Sponsors & Collaborators
-
National Heart, Lung, and Blood Institute (NHLBI)
lead NIH
Principal Investigators
-
Charles W. Hogue, Jr., MD · Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University School of Medicine
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- DOUBLE
Eligibility
- Min Age
- 55 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2001-06-30
- Completion
- 2005-08-31
Countries
- United States
Study Locations
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