MedTrace Logo

Enhanced CJD Surveillance in the Older Population

NCT02629640 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2024-06-10

No results posted yet for this study

Summary

The purpose of this study to investigate if cases of Creutzfeldt-Jakob Disease (CJD) and other forms of prion disease are being missed in older adults living within Lothian.

Conditions

Interventions

OTHER

Medical history questionnaire

Epidemiological review of past medical/dental history; residential history; occupational history; family history of neurodegenerative disease.

OTHER

Clinical assessment and review

History of current illness; neurological examination including general appearance, full cognitive assessment and physical examination; MRI research brain scan.

OTHER

Participant follow-up

Hospital patient management system; regular telephone contact with patient/representative.

OTHER

Blood or buccal sample

Codon-129 genotyping; storage for future research.

OTHER

Post mortem examination

Brain tissue donation to the Edinburgh Brain and Tissue Bank for research,including investigations for evidence of prion disease.

Sponsors & Collaborators

  • NHS Lothian

    collaborator OTHER_GOV

  • Department of Health, United Kingdom

    collaborator OTHER_GOV

  • University of Edinburgh

    lead OTHER

Principal Investigators

  • Anna M Molesworth, PhD · University of Edinburgh

Eligibility

Min Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-01-19
Primary Completion
2022-03-31
Completion
2022-03-31

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02629640 on ClinicalTrials.gov