Trajectory of Recovery in the Elderly
NCT02275026 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 104
Last updated 2021-06-15
Summary
The purpose of this study is to understand how elderly individuals regain their cognitive skills following general anesthesia. The investigators will compare an age stratified group of volunteers who will be evaluated with a series of cognitive tests and a functional MRI. The participants will then be administered general anesthesia for two hours. The investigators will then assess the participants using state of the art tools to determine when participants return to their cognitive baseline.
Conditions
- Delayed Emergence From Anesthesia
- Postoperative Delirium
- Postoperative Cognitive Dysfunction
Interventions
- PROCEDURE
-
Functional magnetic resonance imaging
Diffusion tensor imaging
Sponsors & Collaborators
-
National Institute on Aging (NIA)
collaborator NIH -
Yale University
collaborator OTHER -
Icahn School of Medicine at Mount Sinai
lead OTHER
Principal Investigators
-
Joshua Mincer, MD, PhD · Icahn School of Medicine at Mount Sinai
Study Design
- Allocation
- NA
- Purpose
- SUPPORTIVE_CARE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 40 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2015-07-31
- Primary Completion
- 2020-04-22
- Completion
- 2020-04-22
Countries
- United States
Study Locations
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