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Understanding Pain Perception in Osteoarthritis

NCT02603939 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 250

Last updated 2020-10-26

No results posted yet for this study

Summary

Osteoarthritis (OA)is a painful and disabling disease, predicted to be the fourth largest cause of disability worldwide by 2020. It commonly affects the hip or knee ultimately resulting in total joint replacement. In order to assess disease progression and plan surgery, x-rays are taken as part of routine practice. However x-rays provide limited information about formation of substructures and changes occurring during progression of disease. The proposed study aims to invite patients with OA of the hip or knee to participate in detailed examinations of their pain and their painful joint through interviews, blood and urine samples taken, MRI magnetic resonance imaging)and donating their waste tissue after joint surgery (all of old joint). Informed patient consent will be sought in all cases.

Conditions

Interventions

PROCEDURE

Joint replacement surgery

We are assessing pain responses in participants with osteoarthritis before an after joint replacement surgery

Sponsors & Collaborators

  • St George's, University of London

    lead OTHER

Principal Investigators

  • Nidhi Sofat, MBBS, PhD · St George's, University of London

Eligibility

Min Age
35 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2013-06-30
Primary Completion
2021-12-31
Completion
2022-12-31

Countries

  • United Kingdom

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02603939 on ClinicalTrials.gov