The Relationship Between Chronic OA Pain and Cognition Deficits in OA Patients.
NCT05570240 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 60
Last updated 2022-10-06
Summary
The goal of this observational study is to learn about the association between pain characteristics and cognitive functions in chronic knee osteoarthritis. The main questions it aims to answer are:
1. If pain characteristics affect cognitive functions in severe knee OA patients?
2. If concentration of neuroinflammation mediators were raised in severe knee OA patients with comparing with control group participants?
Participants will receive pain and cognition questionnaire before surgery and their blood and CSF will be collected for further analysis of neuroinflammation mediators.
Conditions
- Knee Osteoarthritis
- Neuroinflammatory Response
Sponsors & Collaborators
-
Kaohsiung Veterans General Hospital.
lead OTHER
Principal Investigators
-
Chun-Hsien Wen, Physician · Kaohsiung Veterans General Hospital.
-
Chen-Hsiu Chen, Physician · Kaohsiung Veterans General Hospital.
-
Yuan-Yi Chia, Director · Kaohsiung Veterans General Hospital.
-
Chih-Chi Tsai, RA · Kaohsiung Veterans General Hospital.
Eligibility
- Min Age
- 20 Years
- Max Age
- 86 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-08-07
- Primary Completion
- 2021-04-21
- Completion
- 2021-04-22
Countries
- Taiwan
Study Locations
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