Early Changes of Diabetes Parameters After Obesity Therapy

Summary

The aim of the study is to investigate, if bariatric surgery or the related caloric restriction causes the significant improvement of glucose metabolism, which has been found in bariatric patients.

Conditions

• Bariatric Surgery Candidate

Interventions

OTHER

Laparoscopic sleeve gastrectomy

The surgical procedure and aftercare is indicated and performed according to the routine clinical setting of the Hospital. Patients stay 5 days stationary after surgical treatment. They receive a defined easy digestible diet, starting with liquid and mash food.

OTHER

Laparoscopic Roux-en-Y gastric bypass

The surgical procedure and aftercare is indicated and performed according to the routine clinical setting of the Hospital. Patients stay 5 days stationary after surgical treatment. They receive a defined easy digestible diet, starting with liquid and mash food.

OTHER

Caloric restriction diet

Patients of the control group do not undergo surgical treatment. They undergo a caloric restriction diet for 5 days. This diet is adapted to the postoperative diet of the patients included in the two other groups.

OTHER

easy digestible diet

Sponsors & Collaborators

• University Hospital Tuebingen

  collaborator OTHER

• Karl-Olga-Krankenhaus Stuttgart

  collaborator UNKNOWN

• University of Hohenheim

  lead OTHER

Principal Investigators

• Stephan C. Bischoff, Prof. · Department of Nutritional Medicine, University of Hohenheim, Stuttgart, Germany

• Alfred Königsrainer, Prof. · Department of General, Visceral, and Transplant Surgery, University Hospital Tübingen, Germany

Study Design

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

FACTORIAL

Eligibility

Min Age

18 Years

Max Age

65 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2015-07-31

Primary Completion

2019-05-31

Completion

2019-07-31

Countries

• Germany

Study Locations