The Role of Multivitamins in Pediatric HIV Management in Nigeria

Summary

Micronutrient deficiencies in people living with HIV have been reported. Multivitamins can address micronutrient deficiencies, however the benefits of multivitamins in people living with HIV is still debatable. While some multivitamin intervention studies have reported the benefits of multivitamins in HIV infection, some other studies have reported no statistical differences in outcomes of interest in intervention and control groups. With clear differences in composition and strength of the multivitamins used in the different studies, it is possible that some of the multivitamins used in some of the intervention studies may have been unable to meet existing micronutrient deficiencies. Hence there is a chance that higher strength multivitamins may be better able to correct these deficiencies and result in better outcomes. This study will therefore compare three different multivitamins varying in strength and composition to determine if any one of the three multivitamins will produce better health outcomes.

Conditions

• HIV

Interventions

DIETARY_SUPPLEMENT

Multivitamin A

Multivitamin containing 7 micronutrients at recommended daily allowance (RDA)

DIETARY_SUPPLEMENT

Multivitamin B

Multivitamin containing 22 micronutrients at RDA

DIETARY_SUPPLEMENT

Multivitamin C

Multivitamin containing 22 micronutrients at three times the RDA

Sponsors & Collaborators

• University of the West of Scotland

  collaborator OTHER

• Brunel Healthcare Manufacturing Limited

  collaborator UNKNOWN

• Partec Nigeria

  collaborator UNKNOWN

• Panets Education Trust for Africa (PETA)

  collaborator UNKNOWN

• Lagos State University

  collaborator OTHER

• Nigerian Institute of Medical Research

  collaborator OTHER_GOV

• Scottish Trace Element and Micronutrient Diagnostic and Research Laboratory, Glasgow

  collaborator UNKNOWN

• Regina Esiovwa

  lead OTHER

Principal Investigators

• Regina Esiovwa · University of the West of Scotland

Study Design

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

QUADRUPLE

Model

PARALLEL

Eligibility

Min Age

5 Years

Max Age

12 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2015-05-31

Primary Completion

2016-02-29

Completion

2016-02-29