Digital Game: A Scale to Evaluate the Perioperative Cognitive Function

Summary

INTRODUCTION: Cognitive dysfunction is a frequent adverse event in the postoperative period, especially in elderly patients. The tests commonly used for the detection of postoperative cognitive dysfunction are time-consuming and with variable sensitivity and specificity and difficult routine use. Applying a difficult battery of cognitive tests decreases the viability of adopting measures to increase preoperative cognitive reserve and methods for prevention, diagnosis and rehabilitation of cases of Postoperative Cognitive Dysfunction (POCD), it is desirable to search for alternative methods diagnoses.

Conditions

• Cognition Disorders
• Impaired Cognition
• Self-Assessment

Interventions

DEVICE

MentalPlus®

Validate the MentalPlus® digital game as neuropsychological test of cognitive assessment pre and postoperative on study the internal consistency and validity of content and construct (convergent) MentalPlus® of the evaluated patients. Study the influence of age, gender and level of education of surgical patients in performance for the use of electronic devices (laptop, tablet, mobile) and digital games. Investigate the rehabilitation capacity of cognitive functions after training sessions with MentalPlus® game. Evaluate the effect of training with MentalPlus® game in brain networks involved in executive function, memory and attention by means of fMRI this is a brain imaging study.

Sponsors & Collaborators

• Fundação de Amparo à Pesquisa do Estado de São Paulo

  collaborator OTHER_GOV

• University of Copenhagen

  collaborator OTHER

• Harvard Medical School (HMS and HSDM)

  collaborator OTHER

• Max Planck Institute for Human Development

  collaborator OTHER

• University of Sao Paulo

  lead OTHER

Principal Investigators

• Lívia SS Valentin, Ph.D. · Faculty of Medicine of the University of Sao Paulo

Study Design

Allocation

RANDOMIZED

Purpose

DIAGNOSTIC

Masking

TRIPLE

Model

PARALLEL

Eligibility

Min Age

20 Years

Max Age

80 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2021-07-08

Primary Completion

2022-07-04

Completion

2023-10-29

Countries

• Brazil

Study Locations