D2D Normative Data for Remote Assessments

Summary

Phase 1: This is a remote observational study in which participants will complete cognitive assessments developed by Posit Science. Participants will be healthy controls aged 18-65 with reliable internet access and a device that they can use to access the assessments, such as a laptop or iPad. Participants will complete up to 6 Posit Science assessments in different domains of cognition, which should last approximately 30 minutes.

Phase 2: This is an in person observational study in which participants will complete cognitive assessments developed by Posit Science. Participants will be healthy controls aged 18-80 who are fluent in English. Participants will complete batteries of cognitive assessments developed by Posit Science, which include combinations of visual, auditory, and social cognitive assessments, and self-report questionnaires. This study will be conducted at the Driven to Discover building at the Minnesota State Fair. Participation will last approximately 20 minutes.

Phase 3: Participants in Phase 3 will complete a Posit Science assessment battery and self-report questionnaires. Each participant will be asked to provide brief demographic and medical history data. Participants will be aged 18-35 and will be students at the University of Minnesota who are enrolled in the Research Experience Points program. Participants will complete the assessment battery remotely; the battery will take approximately 45-60 minutes to complete.

Phase 4: This is a pilot program to test the use of remote cognitive assessment and training in adolescents with an anxiety diagnosis and healthy controls. Participants will complete a short assessment battery, then will receive 4 hours of cognitive training over 2 weeks at home. Then they will repeat the battery. Total participation should last approximately 5 hours over 2-3 weeks and will be completed entirely remotely.

Conditions

• Cognition

Interventions

BEHAVIORAL

Cognitive Assessments (Phase 1)

Participants will participate in up to 6 assessments in 4 domains of cognition: Processing Speed; Executive Attention; Learning and Memory; and Social Cognition. Assessments: * Visual Sweeps * Sustained Visual Attention * Associative Learning--Visual * Associative Learning--Auditory * Emotion Motion * Voice Choice

BEHAVIORAL

Cognitive Battery A (Phase 2)

Participants will complete two visual assessments, one auditory assessment, and one social cognition assessment. Then the participant will complete self-report surveys. Assessments: * On trails: Learning * Line Length Discrimination * Tap the Emotion * Sound Sweeps * BIS/BAS * TEPS * Feasibility survey

BEHAVIORAL

Cognitive Battery B (Phase 2)

Participants will complete two visual assessments, one auditory assessment, and one social cognition assessment. Then the participant will complete the complete self-report surveys. Assessments: * Visual Time Order Judgment * Target Tracker * Emotional Face * Auditory Sound Discrimination * BIS/BAS * TEPS * Feasiblity assessment

BEHAVIORAL

Cognitive Battery C (Phase 2)

Participants will complete two visual assessments, one auditory assessment, and one social cognition assessment. Then the participant willcomplete self-report surveys. Assessments: * Stroop 2AFC * Visual Task Switcher * Beep Seeker * Voice Choice * BIS/BAS * TEPS * Feasibility Survey

Sponsors & Collaborators

• University of California, San Francisco

  collaborator OTHER

• Posit Science Corporation

  collaborator INDUSTRY

• University of Minnesota

  lead OTHER

Principal Investigators

• Sophia Vinogradov, MD · University of Minnesota

Eligibility

Min Age

12 Years

Max Age

80 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2017-06-06

Primary Completion

2019-03-25

Completion

2019-03-25

Countries

• United States

Study Locations