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Aprepitant Versus Gabapentin Prophylaxis for Postoperative Nausea and Vomiting in Laparoscopic Gynecological Surgeries

NCT02525848 · Status: COMPLETED · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 150

Last updated 2016-03-24

No results posted yet for this study

Summary

To evaluate the efficacy of pre-empetive administration of Aprepitant, Versus Gabapentin prophylaxis for reducing the incidence of postoperative nausea and vomiting in Laproscopic gynacological surgeries.

Conditions

  • Postoperative Nausea and Vomiting

Interventions

DRUG

dexamethasone

dexamethasone 8 mg iv 2 minutes before induction of anesthesia

DRUG

Gabapentin

oral gabapentin 600 mg 1 hour before induction of anesthesia

DRUG

Aprepitant

oral aprepitan 80mg 1 hour before induction of anesthesia.

Sponsors & Collaborators

  • Assiut University

    lead OTHER

Principal Investigators

  • Hala S Abdel-Ghaffar, MD · Assisstant professor in Anesthesia and intensive care department, faculty of medicine, Assiut university, Egypt

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-08-31
Primary Completion
2016-03-31
Completion
2016-03-31

Countries

  • Egypt

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02525848 on ClinicalTrials.gov