Circulating Tumor Cells in Operative Blood in Patients With Bladder Cancer
NCT02514408 · Status: WITHDRAWN · Type: OBSERVATIONAL
Last updated 2018-01-02
Summary
This pilot clinical trial studies the impact of radical cystectomy (surgery) on the expulsion (release) of circulating tumor cells into the blood stream in patients with bladder cancer. Significant surgery such as radical cystectomy may cause the expulsion of tumor cells. Studying the release of tumor cells into the circulation may help doctors understand the impact that radical cystectomy has on tumor metastasis and/or tumor recurrence.
Conditions
- Stage II Bladder Urothelial Carcinoma
Interventions
- PROCEDURE
-
Catheter Management
Insertion of venous catheter under ultrasound guidance
- OTHER
-
Cytology Specimen Collection Procedure
Collection of blood samples
- OTHER
-
Laboratory Biomarker Analysis
Correlative studies
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
University of Southern California
lead OTHER
Principal Investigators
-
Inderbir Gill, MD · University of Southern California
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-02-05
- Primary Completion
- 2019-02-05
- Completion
- 2019-03-05
More Related Trials
-
Comparison of Intravesical Therapy and Surgery as Treatment Options for Bladder Cancer 2
NCT07225127 ·Status: RECRUITING
-
Robot-Assisted Laparoscopic High-Intensity Focused Ultrasound and Radical Cystectomy for Thermal Ablation of Muscle Invasive Cells in Patients With Bladder Tumors
NCT03238664 ·Status: WITHDRAWN ·Phase: NA
-
Detection and Clinical Significance of Circulating Cancer Cells in Patient Undergoing Radical Cystectomy
NCT02345473 ·Status: COMPLETED
-
Transurethral Resection and Combination Chemotherapy in Treating Patients With Stage II or Stage III Bladder Cancer
NCT00003640 ·Status: TERMINATED ·Phase: PHASE2
-
Radical Cystectomy Compared With Chemoradiation for Muscle Invasive Bladder Cancer
NCT02716896 ·Status: TERMINATED ·Phase: NA
-
Collecting and Studying Blood and Tissue Samples From Patients With Locally Recurrent or Metastatic Prostate or Bladder/Urothelial Cancer
NCT01050504 ·Status: RECRUITING
-
Ultrasound and Biomarker Tests in Predicting Cancer Aggressiveness in Tissue Samples of Patients With Bladder Cancer
NCT02494635 ·Status: TERMINATED
-
CTC Quantification During TURBT and PKVBT of Transitional Cell Carcinoma in Purging Fluid and Blood
NCT04811846 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
S1011 Standard or Extended Pelvic Lymphadenectomy in Treating Patients Undergoing Surgery for Invasive Bladder Cancer
NCT01224665 ·Status: COMPLETED ·Phase: NA
-
Initial Evaluation of a Telomerase-based Circulating Tumor Cell Assay in Bladder Cancer Cohorts
NCT02246738 ·Status: COMPLETED
-
En-bloc Transurethral Resection of Bladder Tumor (En-bloc TURBT) Specimens Using a Redesigned Surgical Resectoscope Device
NCT04235764 ·Status: RECRUITING
-
Characterizing the Microvascular Environment of Bladder Cancer With Super-Resolution Ultrasound Localization Microscopy
NCT06986304 ·Status: RECRUITING
-
Combination Chemotherapy and Radiation Therapy With/Without Surgery In Patients With Stage II/III Bladder Cancer
NCT00055601 ·Status: COMPLETED ·Phase: PHASE2
-
The Effect of Treatment on Circulating Tumor Cells in Bladder Cancer Patients With Muscle-invasive or Advanced Disease
NCT00829920 ·Status: COMPLETED
-
A Superiority Trial to Compare Re-resection of High-grade T1 Bladder Urothelial Carcinoma to no Re-resection for Improving Progression Free Survival
NCT03266900 ·Status: TERMINATED ·Phase: EARLY_PHASE1
-
A Comparison of the Studer Pouch Versus the T-Pouch Orthotopic Neobladder Urinary Diversion in Bladder Cancer Patients
NCT01008865 ·Status: COMPLETED ·Phase: NA
-
Chemotherapy and Radiation Therapy in Treating Patients With Stage II or Stage III Bladder Cancer That Was Removed by Surgery
NCT00777491 ·Status: COMPLETED ·Phase: PHASE2
-
sEphB4-HSA Before Surgery in Treating Patients With Bladder Cancer, Prostate Cancer, or Kidney Cancer
NCT02767921 ·Status: TERMINATED ·Phase: PHASE1
-
Neoadjuvant Dasatinib and Radical Cystectomy for Transitional Cell Carcinoma of the Bladder
NCT00706641 ·Status: COMPLETED ·Phase: NA
-
Intravesical Adoptive Cell Therapy w/ TIL for BCG Exposed High Grade NMIBC
NCT05768347 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Resiliency in Patients Undergoing Radical Cystectomy for Bladder Cancer
NCT06337305 ·Status: COMPLETED
-
Investigating the Use of a Preoperative High-Arginine Nutritional Supplement Prior to Radical Cystectomy
NCT02655081 ·Status: COMPLETED ·Phase: PHASE2
-
Diagnostic Performance and Predictive Capacity of Immediate Urine Cytology After Transurethral Resection of Non-Muscle Invasive Bladder Cancer; A Prospective Study
NCT04194112 ·Status: COMPLETED ·Phase: NA
-
Cisplatin, Bevacizumab, and Gemcitabine Followed by Surgery, Bevacizumab, and Paclitaxel in Treating Patients With Locally Advanced Nonmetastatic Bladder Cancer That Can Be Removed By Surgery
NCT00268450 ·Status: TERMINATED ·Phase: PHASE2
-
Intravesical BCG Administration to Patients With Invasive Bladder Cancer
NCT02365207 ·Status: TERMINATED ·Phase: NA