Characterizing the Microvascular Environment of Bladder Cancer With Super-Resolution Ultrasound Localization Microscopy
NCT06986304 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 30
Last updated 2026-05-04
Summary
The project will include 30 patients with bladder cancer who are candidates for bladder removal. After signing the consent form, the study team will collect some clinical data, such as age, past medical history, past surgical history, and information about your current disease.
At the day of surgery, after putting participants into sleep and before surgery begins, the study team will do a novel ultrasound called "Super-Resolution Ultrasound Localization Microscopy" to check if there is still disease in the bladder. The team will then compare the results of this investigational ultrasound with the final pathology and other imaging studies.
Conditions
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Michael Abern, M.D. · Duke University
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-10-28
- Primary Completion
- 2027-01-31
- Completion
- 2027-04-30
Countries
- United States
Study Locations
More Related Trials
-
A Multicenter Prospective Cohort Study on Monitoring Recurrence of Urothelial Carcinoma Based on Detection of Urinary Microscopic Residual Disease (MRD)
NCT06991868 ·Status: RECRUITING
-
Cystoscopic Evaluation Predicting pT0 Urothelial Carcinoma of the Bladder
NCT02968732 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Urinary Biomarkers in the Detection of Urothelial Carcinoma of the Bladder
NCT02745301 ·Status: COMPLETED
-
Microbiota in Urine and Urothelium Can be a Factor for Induction of Urinary Bladder Cancer. The Study Will Examine Urine and Bladder Cancer Tissues From Male Patients and Urine of Controls Using Whole Genomic Sequencing Techniques and 16S rRNA. The Aim is to Elucidate Role of Microbiota in Bladder
NCT06289283 ·Status: ACTIVE_NOT_RECRUITING
-
Validation of a Urine-based Assay With Genomic Markers for Predicting Recurrence for Non-muscle Invasive Bladder Cancer
NCT02969109 ·Status: COMPLETED
-
Prediction of Impaired Survival in Elderly Bladder Cancer Patients Opting for Radical Cystectomy
NCT02039310 ·Status: COMPLETED
-
Prognostic Biomarkers in Patients With Urothelial Carcinoma
NCT04872036 ·Status: COMPLETED
-
A Superiority Trial to Compare Re-resection of High-grade T1 Bladder Urothelial Carcinoma to no Re-resection for Improving Progression Free Survival
NCT03266900 ·Status: TERMINATED ·Phase: EARLY_PHASE1
-
a Genome-based Platform to Predict Patients That Can Achieve Bladder Preservation in Muscle Invasive Bladder Cancer Patients
NCT04686149 ·Status: UNKNOWN
-
Diagnostic Performance and Predictive Capacity of Immediate Urine Cytology After Transurethral Resection of Non-Muscle Invasive Bladder Cancer; A Prospective Study
NCT04194112 ·Status: COMPLETED ·Phase: NA
-
Comparison of Intravesical Therapy and Surgery as Treatment Options for Bladder Cancer 2
NCT07225127 ·Status: RECRUITING
-
Care of the Urothelial Cancer Patient and Prospective Procurement of Urothelial Cancer Tissue
NCT02379429 ·Status: RECRUITING
-
Longitudinal Bladder Cancer Study for Tumour Recurrence
NCT05080998 ·Status: RECRUITING
-
Quality of Life After Treatment for Bladder Cancer: The Bladder Cancer Survivorship Study
NCT06350734 ·Status: ACTIVE_NOT_RECRUITING
-
Analysis of Urinary Methylation Patterns Via Liquid Biopsy as an Early Diagnosis Tool
NCT06878027 ·Status: RECRUITING
-
Microbiota in Urine and Urothelium Can be a Factor for Induction of Urinary Bladder Cancer. The Study Will Examine Urine and Bladder Tissues From Egyptian Male Patients and Controls Using Whole Genomic Sequencing Techniques and 16S rRNA. The Aim is to Elucidate Role of Microbiota in Bladder Cancer.
NCT06289270 ·Status: RECRUITING
-
Evaluation of PD-L1 Expression and Immune Infiltration in High-risk Non Muscle Invasive Bladder Cancer
NCT04726735 ·Status: COMPLETED
-
Assessement of the Concordance of Genomic Alterations Between Urine and Tissue in High-Risk NMIBC Patients
NCT04412070 ·Status: TERMINATED
-
Resiliency in Patients Undergoing Radical Cystectomy for Bladder Cancer
NCT06337305 ·Status: COMPLETED
-
Improving Clinical Staging for Muscle Invasive Bladder Cancer Through Molecular Profiling and Improved Imaging
NCT02203136 ·Status: COMPLETED
-
Effect of Tumor Base Size in Bladder Cancer
NCT06632340 ·Status: COMPLETED ·Phase: NA
-
A Study Comparing the Necessity of a Second Transurethral Resection in High-Risk Non-Muscle-Invasive Bladder Cancer Patients With Negative Results From Post-Initial Resection Urine Genome-Wide Low-Depth Sequencing
NCT07036731 ·Status: RECRUITING ·Phase: NA
-
Development and Validation of a Simulator-based Test in Transurethral Resection of Bladder Tumors
NCT03863028 ·Status: COMPLETED
-
Analyzing the Urine During BCG Instillation in Bladder Cancer Patients for Disease Followup
NCT06153849 ·Status: NOT_YET_RECRUITING
-
Mood Alterations in the Patients With Non-Muscle Invasive Bladder Cancer Treated With BCG
NCT05672615 ·Status: RECRUITING