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Chronic Cannabis Smoking, Oxidative Stress and the Pulmonary Innate Immune Response

NCT02480283 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2024-10-10

No results posted yet for this study

Summary

This study plans to evaluate the effects of chronic cannabis smoking on lung health by evaluating its effects on pulmonary health, lung physiology and alveolar macrophage function.

Conditions

  • Cannabis Smoking
  • Oxidative Stress

Interventions

PROCEDURE

Bronchoscopy

Passage of a thin flexible tube through the mouth, into the windpipe and then into the bronchial tubes so that the study doctor can look into the lungs to perform Bronchoalveolar lavage (BAL), cytologic brushing, and protected specimen brushing.

RADIATION

Chest X-ray

To identify any previously undiagnosed lung disease that will either increase the risk of bronchoscopy or confound results of the study.

PROCEDURE

Venipuncture

To collect blood cells and serum for analyses.

PROCEDURE

Intravenous Catheter

To administer the appropriate medications for the bronchoscopy procedure.

Sponsors & Collaborators

  • National Center for Advancing Translational Sciences (NCATS)

    collaborator NIH

  • University of Colorado, Denver

    lead OTHER

Principal Investigators

  • Ellen L Burnham, MD · University of Colorado, Denver

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-11-11
Primary Completion
2026-07-31
Completion
2027-07-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02480283 on ClinicalTrials.gov