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Reduction of Venous Emboli Load After Breathing Normobaric Oxygen Compared to Air

NCT02468752 · Status: COMPLETED · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 48

Last updated 2022-05-27

No results posted yet for this study

Summary

Primary objective:

\- Assessment of venous gas emboli load post diving when breathing normobaric oxygen compared to air.

Secondary objective:

* Assessment of fluid markers of central nervous system injury in blood post diving
* Assessment of fluid markers of inflammation and endothelial dysfunction in blood post diving

Tertiary objective:

\- Assessment of DCS frequency

Conditions

  • Hyperbaric
  • Diving Medicine
  • Decompression Sickness
  • Central Nervous Injury
  • Inflammation
  • Endothelial Dysfunction

Interventions

DRUG

Oxygen

OTHER

Air

Sponsors & Collaborators

  • Swedish Armed Forces Diving and Naval Medicine Centre

    collaborator OTHER

  • KTH Royal Institute of Technology

    collaborator OTHER

  • Sahlgrenska University Hospital

    collaborator OTHER

  • Göteborg University

    lead OTHER

Principal Investigators

  • Mikael Gennser, PhD · Kungliga Tekniska Högskolan, Stockholm, Sweden

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-05-31
Primary Completion
2019-04-30
Completion
2019-04-30

Countries

  • Sweden

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02468752 on ClinicalTrials.gov