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Analysis of Local and Circulating Compounds Released Following Blood Pressure Cuff Inflation

NCT02673957 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 6

Last updated 2020-12-17

No results posted yet for this study

Summary

This study aims to analyze the way the human body responds to a temporary lack of oxygen, or ischaemia. Prospective participants will complete a health screen to confirm overall health / low cardiovascular risk profile.The participants will be required to have pneumatic blood pressure cuff inflation to 200mmHg on the upper arm for 5 minutes which will then be deflated for 5 minutes and then repeating the cycle of inflation and deflation a further 3 times. Blood tests from veins in the forearm would be taken before, during, and after this is done in order to compare results and establish any change in concentration of local and circulating compounds.

Conditions

  • Ischemia

Interventions

OTHER

Blood pressure cuff protocol

4 cycles of pneumatic blood pressure cuff inflation to 200mmHg for 5 minutes followed by 5 minutes of deflation. Each subsequent cycles commences as soon as the previous cycle is completed.

Sponsors & Collaborators

  • University of New England, Australia

    lead OTHER

Principal Investigators

  • Neil Smart, PhD M.Med Sci · University of New England

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-02-29
Primary Completion
2017-05-31
Completion
2017-05-31

Countries

  • Australia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02673957 on ClinicalTrials.gov