Antibiotic Dosing in Pediatric Intensive Care

Summary

Pharmacokinetics of antibiotics in critically ill neonates, infants and children

Conditions

• Pharmacokinetics
• Amoxicillin-clavulanate
• Piperacillin-tazobactam
• Vancomycin
• Teicoplanin
• Meropenem
• Ciprofloxacin
• Amikacin

Interventions

PROCEDURE

blood sampling in patients receiving amoxicillin-clavulanate as part of routine clinical care

PROCEDURE

blood sampling in patients receiving piperacilline-tazobactam as part of routine clinical care.

PROCEDURE

blood sampling in patients receiving vancomycin as part of routine clinical care.

PROCEDURE

blood sampling in patients receiving teicoplanin as part of routine clinical care.

PROCEDURE

blood sampling in patients receiving meropenem as part of routine clinical care.

PROCEDURE

blood sampling and urine smapling in patients receiving ciprofloxacin as part of routine clinical care.

PROCEDURE

blood sampling in patients receiving amikacin as part of routine clinical care.

Sponsors & Collaborators

• University Hospital, Antwerp

  collaborator OTHER

• Queen Fabiola Children's University Hospital (HUDERF/UKZKF)

  collaborator UNKNOWN

• University Hospital, Ghent

  lead OTHER

Principal Investigators

• Pieter De Cock · University Hospital, Ghent

Eligibility

Min Age

1 Day

Max Age

16 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2012-05-31

Primary Completion

2027-09-01

Completion

2027-09-01

Countries

• Belgium

Study Locations