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Efficacy of Cotrimoxazole as a De-escalation Treatment of Ventilator-Associated Pneumonia in Intensive Care Unit

NCT05696093 · Status: RECRUITING · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 628

Last updated 2025-05-20

No results posted yet for this study

Summary

Efficacy of cotrimoxazole as a de-escalation treatment for adult patients Ventilator-Associated Pneumonia in intensive care unit Multicentre randomized non-inferiority trial comparing cotrimoxazole to standard antibiotic therapy for enterobacterial VAP

Conditions

  • Ventilator Associated Pneumonia

Interventions

DRUG

cotrimoxazole

Use of cotrimoxazole therapy for enterobacterial VAP

DRUG

standard antibiotic therapy

Use of standard antibiotic therapy for enterobacterial VAP

Sponsors & Collaborators

  • Assistance Publique - Hôpitaux de Paris

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-10-19
Primary Completion
2026-10-31
Completion
2026-12-31

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05696093 on ClinicalTrials.gov