Pediatric Antibiotic Dosing in Extracorporal Membrane Oxygenation (PADECMO)
NCT06426836 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 300
Last updated 2026-01-16
Summary
Pharmacokinetics of antibiotics in critically ill neonates, infants and children on extracorporeal membrane oxygenation (ECMO).
Conditions
- Pharmacokinetics
- Amoxicillin-clavulanate
- Piperacillin-tazobactam
- Meropenem
- Cefazolin
- Teicoplanin
- Vancomycin
- Ciprofloxacin
- Amikacin
Interventions
- OTHER
-
Amoxicillin-clavulanate
blood sampling in patients receiving amoxicillin-clavulanate as part of routine clinical care
- OTHER
-
Piperacillin-tazobactam
blood sampling in patients receiving piperacillin-tazobactam as part of routine clinical care.
- OTHER
-
Meropenem
blood sampling in patients receiving meropenem as part of routine clinical care.
- OTHER
-
Cefazolin
blood sampling in patients receiving cefazolin as part of routine clinical care.
- OTHER
-
Vancomycin
blood sampling in patients receiving vancomycin as part of routine clinical care.
- OTHER
-
Teicoplanin
blood sampling in patients receiving teicoplanin as part of routine clinical care.
- OTHER
-
Ciprofloxacin
blood sampling and urine sampling in patients receiving ciprofloxacin as part of routine clinical care.
- OTHER
-
Amikacin
blood sampling in patients receiving amikacin as part of routine clinical care.
Sponsors & Collaborators
-
University Hospital, Ghent
lead OTHER
Principal Investigators
-
Annick de Jaeger, MD · University Hospital, Ghent
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- OTHER
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Max Age
- 15 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-08-19
- Primary Completion
- 2026-07-01
- Completion
- 2026-07-01
Countries
- Belgium
Study Locations
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