Understanding the Effect of Metformin on Corus CAD (or ASGES)
NCT02440893 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 37
Last updated 2019-01-31
Summary
The study goal was to understand the effect of Metformin on Age/Sex/Gene Expression Score (ASGES) or Corus CAD (henceforth "Corus") in pre-diabetic patients who are medication naive. This study provided data to determine if the Corus CAD (ASGES) signature was different in pre-diabetic patients when metformin was newly prescribed and taken.
Conditions
- Coronary Artery Disease
- Angina Pectoris
- Chest Pain
- Cardiovascular Diseases
- Coronary Heart Disease
- CAD
- CVD
- CHD
Interventions
- DIAGNOSTIC_TEST
-
Corus CAD (ASGES)
Sponsors & Collaborators
-
CardioDx
lead INDUSTRY
Principal Investigators
-
Mark Mouton, MD · The Mouton Clinic
Eligibility
- Min Age
- 21 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2013-09-30
- Primary Completion
- 2014-06-30
- Completion
- 2014-06-30
More Related Trials
-
The Effects of Metformin on Blood Vessel Structure and Function
NCT00105066 ·Status: COMPLETED ·Phase: PHASE2
-
Metformin's Effect on Glucagon-induced Glucose Production and Protein Metabolism.
NCT01956929 ·Status: COMPLETED ·Phase: PHASE1
-
Metformin Hydrochloride Sustained-release Tablets (Ⅲ) in Patients With Type 2 Diabetes Mellitus Complicated With Coronary Heart Disease
NCT06932874 ·Status: RECRUITING ·Phase: PHASE4
-
Tolerability Study of Liquid Metformin (100 and 250 mg/mL) vs IR Tablets
NCT07300046 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1
-
A Relative Bioavailability Study of Metformin HCl 750 mg ER Tablets Under Non-fasting Conditions
NCT00865852 ·Status: COMPLETED ·Phase: PHASE1
-
Effect of Metformin on Insulin Sensitivity and Pan-Arterial Vascular Function in Adults With Metabolic Syndrome
NCT02633488 ·Status: COMPLETED ·Phase: NA
-
The Effect of Metformin Treatment on Thyroid Hormone Metabolism in Euthyroid Patients With Type 2 Diabetes Mellitus
NCT00463502 ·Status: COMPLETED ·Phase: PHASE4
-
Study of Clinical Response to Acute Metformin By Leveraging Evaluations During a Mixed Meal Tolerance Test for Exploring Glycemia and GeneticS
NCT02087826 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
A Study to Assess the Safety, Tolerability and Glucose-Lowering Efficacy of MK-0893 in Participants With Type 2 Diabetes Mellitus (MK-0893-005)
NCT02004886 ·Status: COMPLETED ·Phase: PHASE2
-
Genomic Outcomes of Metformin
NCT02986659 ·Status: COMPLETED ·Phase: PHASE4
-
The Vascular Effects of Exenatide Versus Metformin in Patients With Pre-Diabetes
NCT00546728 ·Status: COMPLETED ·Phase: PHASE4
-
Metformin and Prevention of Cardiovascular Events in Patients With Acute Myocardial Infarction and Prediabetes (MIMET)
NCT05182970 ·Status: RECRUITING ·Phase: PHASE3
-
The Impact of Metformin on the Outcome of Gouty Arthritis in a Cohort of Egyptian Gouty Patients.
NCT05332795 ·Status: COMPLETED ·Phase: NA
-
Pharmacokinetics of Mitiglinide and Metformin in Free Combination and Fixed-dose Combination in Healthy Male Subjects.
NCT01443221 ·Status: COMPLETED ·Phase: PHASE1
-
Antecedent Metabolic Health and Metformin Aging Study
NCT04264897 ·Status: COMPLETED ·Phase: PHASE3
-
Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans
NCT01762046 ·Status: COMPLETED ·Phase: PHASE1
-
Metformin Use in Rheumatoid Arthritis
NCT03863405 ·Status: UNKNOWN ·Phase: PHASE2
-
Clinical Study to Investigate the Pharmacokinetics and Pharmacodynamics of Metformin in the Elderly
NCT02125305 ·Status: COMPLETED ·Phase: PHASE1
-
A Relative Bioavailability Study of Metformin HCl 750 mg ER Tablets Under Fasting Conditions
NCT00865072 ·Status: COMPLETED ·Phase: PHASE1
-
Assessment of Blood Glucose Changes in Healthy Volunteers After BMS-754807 Alone or BMS-754807 With Metformin
NCT01525823 ·Status: COMPLETED ·Phase: PHASE1
-
Metformin ER 750 mg Tablets, Fed
NCT00834613 ·Status: COMPLETED ·Phase: PHASE1
-
A Clinical Trial to Investigate Safety/Tolerability and Pharmacokinetics of DA-1229_01 Compared to Co-administration of Evogliptin 5 mg and Metformin XR 1000 mg, and to Evaluate the Effect of Food on the Pharmacokinetics of DA-1229_01 in Healthy Male Volunteers
NCT02167061 ·Status: COMPLETED ·Phase: PHASE1
-
Metformin Gastrointestinal Intolerance: Measurement of Mitochondrial Complex I
NCT03445702 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Metformin and Longevity Genes in Prediabetes
NCT01765946 ·Status: COMPLETED ·Phase: PHASE4
-
Pilot Study on Evaluating the Geroprotective Effect of Metformin
NCT06459310 ·Status: RECRUITING ·Phase: PHASE2