Effects of Replacing Diet Beverages With Water on Weight Loss and Plasma Glucose Control in Type 2 Diabetes

Summary

The purpose of the present study is to evaluate the effect of replacing diet beverages with water on weight loss and biochemical indicators for insulin sensitivity and cardiometabolic risk factors of diabetic obese and overweight female adults when they are in a multidisciplinary weight loss plan.

Conditions

• Type 2 Diabetes
• Overweight
• Obese

Interventions

BEHAVIORAL

DBs at the end of the main meal + Diet

Subjects are asked to have 250 ml DBs at the end of their lunch as the main meal, while they are on a multidisciplinary diet plan for 24 weeks.

BEHAVIORAL

Water at the end of the main meal+ Diet

Subjects are asked to have 250 ml water at the end of their lunch as the main meal, while they are on a multidisciplinary diet plan for 24 weeks.

Sponsors & Collaborators

• University of Nottingham

  collaborator OTHER

• Tehran University of Medical Sciences

  collaborator OTHER

• Novindiet Clinic

  lead OTHER

Principal Investigators

• Hamid R Farshchi, MD, PhD · NovinDiet Clinic, School of Life Sciences, The University of Nottingham

• Ameneh Madjd, Dr · NovinDiet Clinic, School of Life Sciences, The University of Nottingham

• Ian A Macdonald, Prof. · School of Life Sciences, The University of Nottingham

• Moira A Taylor, PhD · School of Life Sciences, The University of Nottingham

• Reza Malekzadeh, Prof. · Digestive Disease Research Institute, Tehran University of Medical Sciences

• Alireza Delavari, MD · Digestive Disease Research Institute, Tehran University of Medical Sciences

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

45 Years

Sex

FEMALE

Healthy Volunteers

No

Timeline & Regulatory

Start

2015-04-30

Primary Completion

2015-10-31

Completion

2016-01-31

Countries

• Iran

Study Locations