Pain Predict Genetics

NCT02383342 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 10000

Last updated 2025-08-11

No results posted yet for this study

Summary

Pain is the most frequent cause of suffering and disability in society. Despite considerable involvement of genetic factors in pain sensation and sensitivity, the individual genes involved remain largely unidentified.

In this project the investigators will follow patients undergoing elective major surgery for the development of acute and chronic pain. The investigators will search for clinical as well as genetic factors that can predict the development of pain. These can serve as biomarkers to predict acute and chronic pain development and progression in individual patients and help early individual treatment adaptation.

Conditions

Sponsors & Collaborators

  • Radboud University Medical Center

    lead OTHER

Principal Investigators

  • Han G Brunner, Prof. PhD. · Radboud University Medical Center

  • Barbara Franke, Prof. PhD. · Radboud University Medical Center

  • Gert Jan Scheffer, Prof. PhD. · Radboud University Medical Center

  • Rianne van Boekel, PhD. · Radboud University Medical Center

  • Kris Vissers, PhD · Radboud University Medical Center

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-05-12
Primary Completion
2027-03-31
Completion
2029-03-31

Countries

  • Netherlands

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02383342 on ClinicalTrials.gov