Genetic Origin of Lipid Disorders

Summary

Several lipid disorders are without known genetic origin. The scope of this project is to sequence genes superior involved in lipid and carbohydrate metabolism in patients with severe lipid disorders. The resulting mutations will be tested in suitable in vitro systems to detect their part in development of the specific disease.

Conditions

• Lipid Disorder

Sponsors & Collaborators

• Lipid Clinic, The National Hospital, Oslo, Norway

  collaborator UNKNOWN

• Research Institute of Internal Medicine, The National Hospital, Oslo, Norway

  collaborator UNKNOWN

• Ullevaal University Hospital

  collaborator OTHER

• Norwegian Institute of Public Health

  collaborator OTHER_GOV

• Hormone Laboratory, Aker University Hospital, Oslo, Norway

  collaborator OTHER

• CIGENE, Agricultural University of Norway, Aas, Norway

  collaborator OTHER

• University of Oslo

  lead OTHER

Principal Investigators

• Hilde I Nebb, PhD · Department of Nutrition, University of Oslo

• Karianne Solaas, PhD · Department of Nutrition, University of Oslo

• Monica H Carlsen · Department of Nutrition, University of Oslo

• Leiv Ose, Dr med · Lipid Clinic, The National Hospital

• Marit S Nenseter, PhD · Research Institute of Internal Medicine, The National Hospital

• Kirsten Holven, PhD · Research Institute of Internal Medicine, The National Hospital

• Bente Halvorsen, PhD · Research Institute of Internal Medicine, The National Hospital

• Serena Tonstad, Dr med · Department of Preventive Medicine, Ullevål university hospital

• Håkon Gjessing, PhD · Norwegian Institute of Public Health

• Per Thorsby, Dr med · Hormone laboratory, Aker university hospital

• Sigbjørn Lien, PhD · Agricultural university of Norway

• Paul Berg, PhD · Agricultural university of Norway

• Kjetil Retterstøl, Dr med · Lipid Clinic, The National Hospital

Eligibility

Min Age

18 Years

Max Age

54 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2006-01-31

Countries

• Norway

Study Locations