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Antimicrobial Photodynamic Therapy Applied in Orthodontic. Orthodontic Patients.

NCT02337192 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2015-01-13

No results posted yet for this study

Summary

We demonstrated the use of the Antimicrobial Photodynamic Therapy as a coadjutant oral decontamination agent. It was also shown that SDS surfactant improves the antibacterial action of APDT when using Curcumin as the photosensitizer. The decontamination levels obtained with APDT are comparable with the levels observed with the use of Chlorhexidine. The clinical relevancy is the control of oral microbial load which will improve the patients' quality of life and will decrease the possibility of cross contamination in the dental office.

Conditions

  • Dentist-Patient Relations

Interventions

DRUG

Curcumin

DEVICE

LED

DRUG

Surfactant

DRUG

DMSO + water

DRUG

Chlorhexidine gluconate

Sponsors & Collaborators

  • University of Sao Paulo

    lead OTHER

Principal Investigators

  • Vitor H Panhóca, Ms · University of Sao Paulo

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-01-31
Primary Completion
2014-06-30
Completion
2014-12-31

Countries

  • Brazil

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02337192 on ClinicalTrials.gov