MedTrace Logo

Photodynamic Therapy (PDT) for Oral Disinfection

NCT02152475 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2014-06-03

No results posted yet for this study

Summary

Photodynamic therapy (PDT) is a technique used for the oral disinfection. In dentistry, PDT for microbial inactivation may reduces both dental plaque and risk of developing caries as well as contributes to treat gingivitis, periodontitis, peri-implantitis and endodontic diseases. The investigators hypothesis was that PDT with blue light and curcumin promotes oral disinfection during 2 hours after treatment.

Conditions

  • Healthy

Interventions

DRUG

mouthwash with curcumin

Mouthwash with 20 ml of curcumin solution for 5 minutes

DEVICE

blue LED illumination

Oral cavity was illuminated with blue light for 5 minutes

Sponsors & Collaborators

  • Conselho Nacional de Desenvolvimento Científico e Tecnológico

    collaborator OTHER_GOV

  • Fundação de Amparo à Pesquisa do Estado de São Paulo

    collaborator OTHER_GOV

  • University of Sao Paulo

    lead OTHER

Principal Investigators

  • Vanderlei S Bagnato, Ph.D · Physics Institute of São Carlos (IFSC), University of São Paulo (USP)

  • Diego PV Leite, DDS · Physics Institute of São Carlos (IFSC), University of São Paulo (USP)

  • Fernanda R Paolillo, Ph.D · Physics Institute of São Carlos (IFSC), University of São Paulo (USP)

  • Carla R Fontana, Ph.D · Univ Estadual Paulista (UNESP)

  • Thiago Parmesano, Student · Physics Institute of São Carlos (IFSC), University of São Paulo (USP)

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
35 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2013-05-31
Primary Completion
2013-11-30
Completion
2013-11-30

Countries

  • Brazil

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02152475 on ClinicalTrials.gov