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Evaluation of the Neuro-endocrine Response to Post-prandial Hyperinsulinaemic Hypoglycaemia.

NCT04334161 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 32

Last updated 2021-08-10

No results posted yet for this study

Summary

The primary objective of this study is to assess the neuro-endocrine response to hypoglycaemia in PHH vs. non-PHH post-gastric bypass individuals.

Conditions

  • Roux-en-y Gastric Bypass
  • Post Prandial Hypoglycemia

Interventions

COMBINATION_PRODUCT

Administration of glucose and controlled induction of hypoglycaemia.

Functional metabolic test involving a 15g oral glucose load (enriched with 1.5% U-13C glucose) and subsequent controlled 20min hypoglycaemic clamp period. Neuroendocrine response will be assessed using frequent blood samples for hormones and metabolites, continuous heart rate monitoring and evaluation for hypoglycaemic symptoms.

Sponsors & Collaborators

  • Lia Bally

    lead OTHER

Principal Investigators

  • Lia Bally, MD, PhD · University Hospital Bern & University of Bern

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-10-02
Primary Completion
2021-07-13
Completion
2021-07-13

Countries

  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04334161 on ClinicalTrials.gov