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Influence of Epidural Analgesia on Natural Killer Cell (NK) Activity After Colonic Cancer Surgery

NCT02326727 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2014-12-29

No results posted yet for this study

Summary

Regional anesthesia may decrease the release of endogenous opioids, increase Natural Killer cell (NK) function and decrease development of metastasis. The recent analysis of the Cancer Registry has noted an improved 5-year survival in patients who received epidural analgesia during surgery for colorectal carcinoma.

Conditions

  • Colonic Neoplasms

Interventions

DRUG

Ropivacaine

Epidural analgesia

DRUG

Fentanyl

General Anesthesia

DRUG

Propofol

General Anesthesia

DRUG

Isoflurane

General Anesthesia

DRUG

Nitrous Oxide

General Anesthesia

Sponsors & Collaborators

  • Hillel Yaffe Medical Center

    lead OTHER_GOV

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-04-30
Primary Completion
2017-04-30
Completion
2017-05-31

Countries

  • Israel

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02326727 on ClinicalTrials.gov