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Resting State Functional Magnetic Resonance Imaging Study of Jaundice Infants Before and After Light Treatment.

NCT02224586 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 20

Last updated 2014-08-25

No results posted yet for this study

Summary

It is just an observation study. The investigates want to explore the signal changes of resting state functional Magnetic resonance Imaging (fMRI) after light treatment in jaundice infants. Signal changes contain blood oxygenation level dependent (BOLD) and arterial spin labeling (ASL).Indicator of BOLD is amplitude of low-frequency fluctuation（ALFF).Indicator of ASL is cerebral blood flow (CBF).

The investigates assume that the children with jaundice after light therapy, ALFF and CBF will change. Focus on the globus pallidus and subthalamic nuclei. The two brain regions were proved to be abnormal in MRI T1, T2 structure signal in kernicterus.

Doctors observe the status of infants aside.Using monitoring probe can see clearly.

Conditions

  • Jaundice

Interventions

DEVICE

light treatment

clinical routine treatment according to the doctor's advice

Sponsors & Collaborators

  • Hangzhou Normal University

    lead OTHER

Principal Investigators

  • Ya-Fei Zhu · Center for Cognition and Brain Disorders,Hangzhou Normal University

Eligibility

Min Age
1 Day
Max Age
28 Days
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-08-31
Primary Completion
2015-03-31
Completion
2015-07-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02224586 on ClinicalTrials.gov