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Effect of Probiotic Lozenge on Gingivitis and Periodontitis

NCT02203812 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 32

Last updated 2016-07-27

No results posted yet for this study

Summary

The oral cavity is mostly influenced by general health. The oral microbiota which is as complex as the gastro-intestinal or vaginal microbiota are considered to be difficult therapeutic targets. The effects of probiotics in different fields of health care have resulted recently in the introduction of probiotics for oral healthcare. Probiotics have been clinically proved effective in different fields of oral healthcare such as halitosis, oral candidiasis and tooth decay. They have also been inducted in the field of periodontal healthcare because of the current views on the etiology of plaque- related periodontal inflammation.

Conditions

  • Mild and Moderate Chronic Periodontitis

Interventions

DRUG

Probiotic Arm

Each Inersan lozenge contains at least 1 billion colony forming unit of Lactobacillus brevis CD2

DRUG

Placebo Arm

Placebo lozenges contain all ingredients except the active constituent (probiotic, Lactobacillus brevis CD2)

Sponsors & Collaborators

  • Government Dental College and Hospital, Vijayawada, Andra Pradesh, India

    collaborator UNKNOWN

  • CD Pharma India Pvt. Ltd.

    lead INDUSTRY

Principal Investigators

  • Surya Jyotsna Kiran Kanchumurthy, BDS · Government Dental College and Hospital, Vijayawada, Andhra Pradesh

  • Narendra Dev Jampani, MDS · Government Dental College and Hospital, Vijayawada, Andhra Pradesh

  • Vajra Madhuri S, MDS · Government Dental College and Hospital, Vijayawada, Andhra Pradesh

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-01-31
Primary Completion
2016-02-29
Completion
2016-05-31

Countries

  • India

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02203812 on ClinicalTrials.gov