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Effect of a Probiotic Water on Oral Health in Adults

NCT04473404 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 48

Last updated 2020-09-04

No results posted yet for this study

Summary

The purpose of this study is to evaluate the effects of consuming a probiotic on salivary, plaque, and tongue bacteria, as well as oral malodor (bad breath). Healthy volunteers will consume a probiotic powder, or a placebo powder, that is dissolved in water for 4 weeks.

Conditions

  • Oral Bacteria
  • Halitosis

Interventions

DIETARY_SUPPLEMENT

Streptococcus salivarius DB-B5 - 2 billion CFU/day

The participants (n=15) will consume sachets containing Streptococcus salivarius DB-B5 (at 1 billion CFU/sachet) dissolved in water twice daily for 4 weeks.

DIETARY_SUPPLEMENT

Streptococcus salivarius DB-B5 - 10 billion CFU/day

The participants (n=15) will consume sachets containing Streptococcus salivarius DB-B5 (at 5 billion CFU/sachet) dissolved in water twice daily for 4 weeks.

OTHER

Placebo

The participants (n=15) will consume sachets containing a placebo (probiotic carrier) twice daily for 4 weeks.

Sponsors & Collaborators

  • Dose Biosystems Inc.

    lead INDUSTRY

Principal Investigators

  • Jeffery L. Milleman, DDS, MPA · Salus Research, Inc.

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-07-20
Primary Completion
2020-08-26
Completion
2020-08-26

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04473404 on ClinicalTrials.gov