MedTrace Logo

Effect of Probiotic on the Plaque pH. A Randomized Double Blind Interventional Study

NCT01601145 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 192

Last updated 2012-08-22

No results posted yet for this study

Summary

The aim of the present research protocol was to evaluate the effect of probiotics daily used, on the plaque acidogenicity of children. The null hypothesis was that the plaque acidogenicity would remain unchanged and not associate with the use of probiotics. Moreover, the in situ study will be carried out to investigate the plaque formation as biofilm in demineralised enamel specimens following the regular consumption of a probiotic product compared to a control group. Metabolic of the biofilm formed on of the enamel specimens resulting from the consumption will be evaluated over a period of 8 weeks.

Conditions

  • Plaque Ph Lowering After Use of Probiotics
  • Caries
  • Gingivitis

Interventions

DIETARY_SUPPLEMENT

consumption of lozenges

Each subject two lozenges a day for 6 weeks

Sponsors & Collaborators

  • Università degli Studi di Sassari

    lead OTHER

Principal Investigators

  • Guglielmo Campus · University of Sassari, Dept of Surgery, Microsurgery and Medicine Sciences

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
6 Years
Max Age
8 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-01-31
Primary Completion
2012-07-31
Completion
2012-08-31

Countries

  • Italy

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01601145 on ClinicalTrials.gov