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Evaluation of the Effects of Probiotic Toothpastes on Periodontal Health

NCT06514664 · Status: ENROLLING_BY_INVITATION · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2025-03-11

No results posted yet for this study

Summary

This controlled, randomized clinical study aims to evaluate the possible effects of probiotic toothpaste on the success of periodontal treatment in smokers and non-smokers with clinical data.

The main question(s) it aims to answer are:

Does applying probiotic toothpaste in addition to periodontal treatment have a positive effect on the gingival of periodontitis patients who are smokers and non-smokers?

The study includes four groups; Group 1: Use of probiotic toothpaste + smoking patient Group 2: Use of regular toothpaste + smoking patient Group 3: Use of probiotic toothpaste + non-smoking patient Group 4: Use of regular toothpaste + non-smoking patient

Conditions

  • Periodontal Diseases
  • Periodontitis
  • Gingivitis

Interventions

OTHER

Using Probiotic Toothpaste

Scaling and root planing (Phase 1 = non-surgical periodontal treatment) are performed in all patient groups. Depending on the study groups, regular or probiotic toothpaste will be used. Toothpaste is instructed to be used twice a day

Sponsors & Collaborators

  • Kutahya Health Sciences University

    lead OTHER

Principal Investigators

  • Berceste Guler Ayyildiz · Kutahya Health Science University

  • Ahu Uraz Corekci · Izmir Democracy University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
99 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-04-10
Primary Completion
2025-09-10
Completion
2025-12-10

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06514664 on ClinicalTrials.gov