Remote Preconditioning Over Time To Empower Cerebral Tissue
NCT02169739 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 6
Last updated 2021-03-10
Summary
Previous studies in animals and humans has shown that brief periods of reduced blood flow to one organ or tissue in the body can help protect other tissues from subsequent injury caused by reduced blood flow such as a stroke. This phenomenon is known as remote ischemic preconditioning and may help protect brain cells after a stroke. The investigators are studying a specific stroke type called subcortical stroke that is very common and has a high rate of recurrent stroke and cognition problems despite intensive prevention measures.
Conditions
- Ischemic Stroke
- Cerebral Small Vessel Disease
- Cognitive Decline
Interventions
- DEVICE
-
Ischemic Preconditioning
Patients will undergo ischemic preconditioning once or twice daily for up to four 5-minutes cycles of bilateral upper extremity ischemia separated by 5-minute periods of reperfusion.
Sponsors & Collaborators
- collaborator OTHER
-
University of California, Los Angeles
lead OTHER
Principal Investigators
-
Latisha K Sharma, MD · University of California, Los Angeles
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 40 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2015-11-30
- Primary Completion
- 2020-03-31
- Completion
- 2020-03-31
Countries
- United States
Study Locations
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