Photodynamic in Periodontal Treatment
NCT05162417 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 18
Last updated 2023-11-29
Summary
Dental biofilm is a primary etiological factor for periodontal diseases.(1) The bacterial biofilm would induce recruitment of leucocytes, neutrophils, and T lymphocytes and the secretion of antibodies, lipopolysaccharides, and chemical inflammatory mediators such as cytokines and chemokines.(2) Thus, periodontal diseases can cause tissue destruction and results in deterioration of clinical parameters measures such as periodontal pockets depth, clinical attachment loss, bleeding on probing, bone destruction, and resulting ultimately in tooth loss.(3)
Conditions
- Periodontal Diseases
- Periodontal Pocket
Interventions
- OTHER
-
Methylene Blue
1mg/ml of Methylene as a solution will be used two times, first immediately after scaling and root planning, second after two weeks of the first treatment.
- OTHER
-
Toluidine Blue O
1mg/ml of Toluidine blue o as a solution will be used two times, first immediately after scaling and root planning, second after two weeks of the first treatment.
Sponsors & Collaborators
-
University of Sulaimani
lead OTHER
Principal Investigators
-
Sarhang S. Gul, PhD · College of Dentistry, University of Sulaimani
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2021-11-15
- Primary Completion
- 2022-11-01
- Completion
- 2023-04-01
Countries
- Iraq
Study Locations
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