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Composition & Function of Sarcoplasmic Reticulum in Persons With the Metabolic Syndrome

NCT02122666 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 27

Last updated 2024-10-26

Study results available
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Summary

The investigators previous research has suggested that lipid (fatty) composition in the muscle cells of mice plays a key role in their insulin sensitivity. The purpose of this study is to determine whether these specific fat signatures translate to humans by comparing the muscle of healthy patients to those with pre-diabetes, or "the metabolic syndrome".

Conditions

  • Metabolic Syndrome

Interventions

PROCEDURE

muscle biopsy

A member of the study team will obtain a small sample of muscle tissue from the patient's thigh (vastus lateralis muscle).

Sponsors & Collaborators

  • Washington University School of Medicine

    lead OTHER

Principal Investigators

  • Clay F. Semenkovich, M.D. · Washington University School of Medicine

  • Janet B McGill, M.D. · Washington University School of Medicine

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-03-31
Primary Completion
2024-02-15
Completion
2024-02-15

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02122666 on ClinicalTrials.gov