Effects of Coffee Consumption on Glucose Metabolism

Summary

Epidemiological studies have shown an inverse association between coffee consumption and risk of type 2 diabetes mellitus (T2DM). However the experimental studies that analysed the mechanisms are limited.

This project aims to assess the effects of coffee consumption on glucose metabolism, using stable isotope tracer (13C-glucose) to explain the possible metabolic mechanisms involved on the reduced risk for T2DM.

Conditions

• Healthy

Interventions

OTHER

Coffee with Sugar

300mL of Coffee with 30g of Sugar

OTHER

Coffee without Sugar

300mL of Coffee without Sugar

OTHER

Decaffeinated Coffee without Sugar

300mL of Decaffeinated Coffee without Sugar

OTHER

Water with Sugar

300mL of Water with 30g of Sugar

OTHER

Water without Sugar

300mL of Water without Sugar

Sponsors & Collaborators

• Conselho Nacional de Desenvolvimento Científico e Tecnológico

  collaborator OTHER_GOV

• MRC Human Nutrition Research

  collaborator OTHER_GOV

• University of Brasilia

  lead OTHER

Principal Investigators

• Leslie JC Bluck, PhD · MRC Human Nutrition Research

• Teresa HM da Costa, PhD · University of Brasilia

• Caio EG Reis, MSc · University of Brasilia

Study Design

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

SINGLE

Model

CROSSOVER

Eligibility

Min Age

18 Years

Max Age

50 Years

Sex

MALE

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2012-06-30

Primary Completion

2013-12-31

Completion

2013-12-31

Countries

• Brazil

Study Locations