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Vitamin E and Male Infertility

NCT00178516 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 58

Last updated 2009-07-30

No results posted yet for this study

Summary

The goal of this study is to determine whether there is a correlation between the levels of Vitamin E in sperm and sperm DNA fragmentation.

Previous research has shown that damage to the DNA in sperm may cause infertility or increase the chances of miscarriage, if the damage is extensive (eg. present in the overwhelming majority of sperm). Some studies suggest that DNA damage can be caused by oxidative stress. Antioxidants, such as Vitamin E, which are present in some foods, can prevent damage to cells from "free radicals", which are naturally present by-products of metabolism. We ask whether there is a correlation between sperm DNA damage and Vitamin E

Conditions

  • Male Infertility

Interventions

OTHER

behavior, procedure

Sponsors & Collaborators

  • Mae Stone Goode Foundation

    collaborator OTHER

  • University of Rochester

    lead OTHER

Principal Investigators

  • Vivian Lewis, MD · University of Rochester

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2004-06-30
Primary Completion
2005-12-31
Completion
2005-12-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00178516 on ClinicalTrials.gov