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Inflammatory Markers in Obstructive Sleep Apnea (OSA) Patients.

NCT03070769 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 1053

Last updated 2017-03-06

No results posted yet for this study

Summary

The aim of our study was to assess the levels of inflammatory biomarkers in a large sample of OSA patients and to investigate any correlation between these markers with clinical and polysomnographic (PSG) parameters.

Subjects undergone a PSG for OSA diagnosis were recruited. Patients with known comorbidities were excluded from the study. Included patients were grouped according to apnea-hypopnea index (AHI) as mild, moderate and severe. Patients with AHI \< 5 served as control group. Demographic, PSG data, serum levels of hs-C-reactive protein (hs-CRP), fibrinogen, erythrocyte sedimentation rate (ESR) and Uric Acid (UA) were measured and compared between groups.

Conditions

  • Obstructive Sleep Apnea of Adult

Interventions

PROCEDURE

Venous blood collection for biomarkers measurements

Venous blood was collected in all subjects for measurements of hs-C-reactive protein (hs-CRP), fibrinogen, erythrocyte sedimentation rate (ESR) and Uric Acid (UA) between 8:00 and 9:00 AM, following an overnight fast, shortly after the conclusion of the overnight polysomnography (PSG).

Sponsors & Collaborators

  • University of Crete

    lead OTHER

Principal Investigators

  • Sophia Schiza, MD, PhD · University of Crete

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-06-01
Primary Completion
2016-06-01
Completion
2016-12-12

Countries

  • Greece

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03070769 on ClinicalTrials.gov