Obstructive Sleep Apnea and Genes Expression
NCT01392339 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 35
Last updated 2011-07-12
Summary
Obstructive sleep apnea is a multi-component disease. This study will test the hypotheses that hypoxia per se modulates gene expression in animal model of sleep apnea and these results may be translated with alterations that occur in apneic patients. Thus, we aim to integrate basic and clinical research to shed light on novel candidate genes involved in sleep apnea.
Conditions
Interventions
- PROCEDURE
-
Continuous Positive Airway Pressure (CPAP)
Continuous Positive Airway Pressure (CPAP) is a method of respiratory ventilation used primarily in the treatment of obstructive sleep apnea
Sponsors & Collaborators
-
Conselho Nacional de Desenvolvimento Científico e Tecnológico
collaborator OTHER_GOV -
Fundação de Amparo à Pesquisa do Estado de São Paulo
collaborator OTHER_GOV -
Associacao Fundo de Incentivo a Psicofarmcologia
lead OTHER
Principal Investigators
-
Juliana C Perry, PhD · Federal University of São Paulo
-
Lia Rita A Bittencourt, MD, PhD · Associacao Fundo de Incentivo a Psicofarmacologia
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- SINGLE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 30 Years
- Max Age
- 60 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2011-02-28
- Primary Completion
- 2011-07-31
- Completion
- 2011-10-31
Countries
- Brazil
Study Locations
More Related Trials
-
Continuous Positive Airway Pressure (CPAP), Oral Appliance and Physical Exercise in the Obstructive Sleep Apnea
NCT01289392 ·Status: COMPLETED ·Phase: NA
-
Dissection of Differentially Expressed Genes and Pathways in Patients With OSAS Before and After CPAP Treatment
NCT00498732 ·Status: COMPLETED
-
Obstructive Sleep Apnea and Telomere Length
NCT04872816 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluation of Potential Biomarkers for Obstructive Sleep Apnea and the Effect of Positive Pressure Treatment
NCT01976052 ·Status: COMPLETED
-
Continuous Positive Airway Pressure and Oral Appliances Treatments in Mild Obstructive Sleep Apnea
NCT01461486 ·Status: COMPLETED ·Phase: NA
-
Titration of Continuous Positive Airway Pressure Could Predict Success of Oral Appliance to Treat Sleep Apnea
NCT01336556 ·Status: UNKNOWN ·Phase: NA
-
Phonoaudiologic Therapy Adjunct to Treatment on Patients With Obstructive Sleep Apnea
NCT01289405 ·Status: COMPLETED ·Phase: NA
-
A Prospective Observational Cohort to Study the Genetics of Obstructive Sleep Apnea and Associated Co-Morbidities
NCT01857427 ·Status: ACTIVE_NOT_RECRUITING
-
Efficacy of CPAP Treatment on Blood Pressure of Resistant Hypertension Patients With Obstructive Sleep Apnea Syndrome
NCT01508754 ·Status: COMPLETED ·Phase: PHASE4
-
The Impact of Sleep Apnea Treatment on Physiology Traits in Chinese Patients With Obstructive Sleep Apnea
NCT02696629 ·Status: UNKNOWN
-
The Effects of Continuous Positive Airway Pressure (CPAP) on Sympathetic Activity in Different Sites of Activation
NCT01336335 ·Status: UNKNOWN ·Phase: PHASE3
-
The Changes of Patterns of Microarray in Patients With Obstructive Sleep Apnea
NCT00498849 ·Status: UNKNOWN ·Phase: NA
-
Polymorphisms in Inflammatory Cytokines Genes in Subjects With Obstructive Sleep Apnea
NCT00395590 ·Status: UNKNOWN
-
Biological and Cognitive Marker of Neurodegeneration in Obstructive Sleep Apnea Patients
NCT06167369 ·Status: RECRUITING
-
Outcome and Treatment of Complex Sleep Apnea
NCT01137214 ·Status: WITHDRAWN ·Phase: PHASE2
-
Early Signs of Atherosclerosis in Obstructive Sleep Apnea: Effects of Treatment
NCT00400543 ·Status: COMPLETED ·Phase: PHASE4
-
Structural and Functional Left Ventricular Remodelling in Patients With Obstructive Sleep Apnea
NCT00768807 ·Status: COMPLETED ·Phase: NA
-
Clinical Characteristics and Molecular Mechanism of Patients With Obstructive Sleep Apnea
NCT07277608 ·Status: RECRUITING
-
Effect of Obstructive Sleep Apnea on Central Blood Pressure and Kidney and Endothelial Function
NCT00947479 ·Status: UNKNOWN ·Phase: NA
-
Impact of Obstructive Sleep Apnea Treatment in Patients With Metabolic Syndrome
NCT02295202 ·Status: COMPLETED ·Phase: PHASE4
-
Effect of Continuous Positive Airway Pressure on Chronotype, Dietary Intake, and Cardiovascular Risk Markers
NCT04262960 ·Status: UNKNOWN ·Phase: NA
-
Cardiovascular Risk Stratification in Patients With Obstructive Sleep Apnea
NCT00768625 ·Status: UNKNOWN
-
Identification of Biomarkers for Obstructive Sleep Apnoea Syndrome
NCT02043483 ·Status: COMPLETED
-
Metabolic Profiling in Patients With Obstructive Sleep Apnea: From Plasma to Hypoxic Cell Model of Peripheral Monocyte
NCT02130050 ·Status: UNKNOWN
-
Effects of CPAP Therapy on Blood Pressure and Heart Rate Variability in Obstructive Sleep Apnea
NCT04712656 ·Status: RECRUITING