A Study Evaluating Veliparib as a Single Agent or in Combination With Chemotherapy in Subjects With Solid Tumors
NCT02033551 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 47
Last updated 2016-09-27
Summary
This is an extension study to evaluate the safety of Veliparib monotherapy or in combination with Carboplatin plus Paclitaxel or modified Folinic Acid/Fluorouracil/Irinotecan (FOLFIRI) in subjects with solid tumors.
Conditions
Interventions
- DRUG
-
Veliparib
- DRUG
- DRUG
- DRUG
-
combination of Fluorouracil, leucovorin and irinotecan
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Stacie Shepherd, PhD · AbbVie
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 99 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2013-12-31
- Primary Completion
- 2016-09-30
- Completion
- 2016-09-30
Countries
- United States
- Netherlands
- Spain
Study Locations
More Related Trials
-
A Study Evaluating the Safety and Pharmacokinetics of ABBV-075 in Subjects With Cancer
NCT02391480 ·Status: COMPLETED ·Phase: PHASE1
-
A Study With ABBV-155 Alone and in Combination With Taxane Therapy in Adults With Relapsed and/or Refractory Solid Tumors
NCT03595059 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of ABT-165 in Subjects With Solid Tumors
NCT01946074 ·Status: COMPLETED ·Phase: PHASE1
-
A Study Evaluating the Safety, Pharmacokinetics (PK), and Preliminary Efficacy of ABBV-399 in Participants With Advanced Solid Tumors
NCT02099058 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Study of APR-1051 in Patients With Advanced Solid Tumors
NCT06260514 ·Status: RECRUITING ·Phase: PHASE1
-
A Study of the Safety and Tolerability of ABBV-621 in Participants With Previously-Treated Solid Tumors and Hematologic Malignancies
NCT03082209 ·Status: COMPLETED ·Phase: PHASE1
-
An Extension Study for Patients Previously Enrolled in Studies With Pelabresib
NCT06401356 ·Status: RECRUITING ·Phase: PHASE3
-
A Study Using Olaparib Tablets for Subjects With Advanced Solid Tumours.
NCT03553108 ·Status: COMPLETED ·Phase: PHASE1
-
A Dose Escalation Study of Iniparib as a Single Agent and in Combination in Solid Tumors
NCT01455532 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Assess the Blood Levels and Safety of Olaparib in Patients With Advanced Solid Tumours and Normal or Impaired Kidney Function
NCT01894256 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Determine the Safety, Tolerability, Pharmacokinetics and Recommended Phase 2 Dose (RP2D) of Livmoniplimab (ABBV-151) as a Single Agent and in Combination With Budigalimab (ABBV-181) in Participants With Locally Advanced or Metastatic Solid Tumors
NCT03821935 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
First-Time-in-Human Study of GSK4381562 in Participants With Advanced Solid Tumors
NCT05277051 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Study to Evaluate Adverse Events, Change in Disease Activity, and How ABBV-706 Moves Through the Body When Intravenously (IV) Infused Alone or in Combination With IV Infused Budigalimab, Cisplatin, or Carboplatin in Adult Participants With Advanced Solid Tumors
NCT05599984 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
A Phase 1 Study of CC-486 as a Single Agent and in Combination With Carboplatin or ABI-007 in Subjects With Relapsed or Refractory Solid Tumors
NCT01478685 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of the Safety and Efficacy of Atezolizumab Administered in Combination With Bevacizumab and/or Other Treatments in Participants With Solid Tumors
NCT02715531 ·Status: COMPLETED ·Phase: PHASE1
-
Study of STK-012 Alone and With Other Treatments in Patients With Advanced Lung Cancer and Other Cancers
NCT05098132 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Study of Olaparib and Durvalumab in IDH-Mutated Solid Tumors
NCT03991832 ·Status: RECRUITING ·Phase: PHASE2
-
A Study of Budigalimab (ABBV-181) in Participants With Advanced Solid Tumors
NCT03000257 ·Status: COMPLETED ·Phase: PHASE1
-
Study of Cabozantinib Alone or in Combination With Atezolizumab to Subjects With Locally Advanced or Metastatic Solid Tumors
NCT03170960 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
A Study to Assess the Safety, Pharmacokinetics, and Efficacy of Intravenous (IV) ABBV-303, as Monotherapy and in Combination With IV Infused Budigalimab (ABBV-181), in Adults With Advanced Solid Tumors
NCT06158958 ·Status: TERMINATED ·Phase: PHASE1
-
A Study to Test Different Doses of BI 1831169 Alone and in Combination With an Anti-PD-1 Antibody in People With Different Types of Advanced Cancer (Solid Tumors)
NCT05155332 ·Status: SUSPENDED ·Phase: PHASE1
-
A Study of ABBV-428, an Immunotherapy, in Subjects With Advanced Solid Tumors
NCT02955251 ·Status: COMPLETED ·Phase: PHASE1
-
Testing the Combination of the Anti-cancer Drugs Copanlisib, Olaparib, and MEDI4736 (Durvalumab) in Patients With Advanced Solid Tumors With Selected Mutations
NCT03842228 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Phase 1/2a Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of WEF-001 as Monotherapy in Advanced KRAS-Mutant Solid Tumours.
NCT07148128 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors, Receiving Intravenous Infusion of Azirkitug Alone or in Combination(s) With Budigalimab, Bevacizumab, or Telisotuzumab Adizutecan
NCT05005403 ·Status: RECRUITING ·Phase: PHASE1