An Optimized Programming of Healthy Children (APPROACH)

Summary

The Nutrition Research Unit at Copenhagen University Hospital Herlev will during the fall 2013 initiate a randomized and controlled intervention study engaging 390 obese pregnant women. The overall aim of APPROACH is to investigate how an optimal diet during pregnancy influences the programming of the offspring. The children will after birth be included in a prospective cohort according to maternal randomization and examined six times from delivery until the age of nine years.

Conditions

• Pregnancy
• Obesity
• Gestational Age and Weight Conditions
• Maternal Care for Excessive Fetal Growth
• Metabolic Disorders

Interventions

OTHER

High-Protein/Low-GI Diet

OTHER

Low-protein/High-GI Diet

Sponsors & Collaborators

• The Danish Dairy Research Foundation, Denmark

  collaborator OTHER

• Nordea-Fonden, Denmark

  collaborator UNKNOWN

• LEGO Charity, Denmark

  collaborator UNKNOWN

• Pharma Nord

  collaborator INDUSTRY

• Danish Agriculture and Food Council

  collaborator OTHER

• Danish Pork Levy Foundation

  collaborator UNKNOWN

• The Novo Nordic Foundation

  collaborator OTHER

• University of Copenhagen

  lead OTHER

Principal Investigators

• Christian Mølgaard, Professor · Department of Nutrition, Exercise and sports, University of Copenhagen

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

42 Years

Sex

FEMALE

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2014-01-04

Primary Completion

2018-01-31

Completion

2027-12-31

Countries

• Denmark

Study Locations