Genotype-Phenotype Associations in Pediatric Cardiomyopathy (PCM GENES)

Summary

Cardiomyopathy in children is a serious disease which can result in death, disability, heart transplantation or serious heart rhythm disorders. Doctors know little about the causes of cardiomyopathy but would like to learn more. In fact, up to 50-75% of cases in children have no known cause. For this reason, the purpose of this study is to identify genes that cause cardiomyopathy or that influence how people with cardiomyopathy do over time. These findings could improve disease prevention, surveillance, early management, and prognosis.

Conditions

• Dilated Cardiomyopathy
• Hypertrophic Cardiomyopathy
• Restrictive Cardiomyopathy

Sponsors & Collaborators

• Carelon Research

  collaborator OTHER

• Children's Hospital Medical Center, Cincinnati

  collaborator OTHER

• Washington University School of Medicine

  collaborator OTHER

• Children's Hospital of Philadelphia

  collaborator OTHER

• Columbia University

  collaborator OTHER

• Boston Children's Hospital

  collaborator OTHER

• Ann & Robert H Lurie Children's Hospital of Chicago

  collaborator OTHER

• Primary Children's Hospital

  collaborator OTHER

• Monroe Carell Jr. Children's Hospital at Vanderbilt

  collaborator OTHER

• Stollery Children's Hospital

  collaborator OTHER

• National Heart, Lung, and Blood Institute (NHLBI)

  collaborator NIH

• University of Miami

  collaborator OTHER

• Children's Hospital Colorado

  collaborator OTHER

• Indiana University

  collaborator OTHER

• Wayne State University

  lead OTHER

Principal Investigators

• Steven E Lipshultz, MD · Wayne State University

Eligibility

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2013-04-30

Primary Completion

2017-02-28

Completion

2018-03-31

Countries

• United States
• Canada

Study Locations