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Extubation Failure Prevention in High Risk Patients by High-flow Conditioned Oxygen Therapy vs. Standard Oxygen Therapy

NCT01820507 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 155

Last updated 2015-01-30

No results posted yet for this study

Summary

Failure of extubation after mechanical ventilation is a frequent and deleterious issue. Main reasons for failure are hypoxemia, secretions retention, lung collapse and excessive work of breathing. Most of this issues can be partly counterbalanced by a device named "High flow conditioned oxygen therapy (HFCO)". Then, our hypothesis is that HFCO may reduce the incidence of respiratory failure after extubation in patients with high risk for failure.

Conditions

Interventions

DEVICE

Optiflow (Fisher&Paykel)

The described method of oxygen supply will be maintained continuously for the first 24 hours after extubation.

DEVICE

Nasal cannulae or controlled oxygen concentration mask

The described method of oxygen supply will be maintained continuously for the first 24 hours after extubation.

Sponsors & Collaborators

  • Althaia Xarxa Assistencial Universitària de Manresa

    lead OTHER

Principal Investigators

  • Rafael Fernandez, MD · Fundacio Althaia

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
95 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-03-31
Primary Completion
2014-11-30
Completion
2015-01-31

Countries

  • Spain

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01820507 on ClinicalTrials.gov