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DHA & Lutein and fMRI Brain Mapping in Healthy Children

NCT01789866 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 62

Last updated 2023-08-18

No results posted yet for this study

Summary

Studies suggest that lutein and n-3 fatty acids may influence the development of a child's brain and may be related to how well children learn. Both lutein and the n-3 fats (also known as omega-3 fats) are not made by the body and must be obtained in the diet. The investigators are interested to understand the importance of n-3 fats and lutein to child brain development. Functional magnetic resonance imaging (fMRI) will make it possible to look into the brain from the outside and see which parts of the brain are being used as children complete working memory tasks. The investigators will study brain function using fMRI among children with different intakes of n-3 fats and lutein.

Hypothesis:

1. Children 6 years of age consuming \< 25 mg/day DHA and \< 400 μg lutein/day will show poorer activation of brain areas on fMRI than children consuming \> 150 mg/day DHA and \> 1,200 μg/day lutein.
2. Children consuming \< 400 μg lutein/day and \> 150 mg/day DHA will also show differences in fMRI results when compared to children consuming \> 150 mg/day DHA and \> 1,200 μg/day lutein.

Conditions

  • Healthy Nutrition

Sponsors & Collaborators

  • University of British Columbia

    lead OTHER

Principal Investigators

  • Sheila M Innis, PhD · Child & Family Research Institute, University of British Columbia

Eligibility

Min Age
69 Months
Max Age
78 Months
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-09-30
Primary Completion
2015-01-31
Completion
2015-01-31

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01789866 on ClinicalTrials.gov